Thalidomide-5-PEG3-NH2 239T7519 Hydrochloride Genetic suppression screens identifi ed

Genetic suppression screens identifi ed enforcers of the spindle-assembly checkpoint (SAC) as essential for LY3295668 cytotoxicity in RB1-defi cient cancers and suggest a model in which a primed SAC creates a unique dependency on AURKA for mitotic exit and survival

InChiKey: ONDPWWDPQDCQNJ-UHFFFAOYSA-N

also known as levallorphan tartate (USAN)

the derivative of EMI1

Thalidomide-5-PEG3-NH2 239T7519 Hydrochloride Genetic suppression screens identifi edThalidomide 5 PEG3 NH2 is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Product information Molecular Weight: 405. 40 Formula: C19H23N3O7 Chemical Name: 5 {2 [2 (2 aminoethoxy)ethoxy]ethoxy} 2 (2, 6 dioxopiperidin 3 yl) 2, 3 dihydro 1H isoindole 1, 3 dione Smiles: NCCOCCOCCOC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: XMTFEXSNGIBNRG UHFFFAOYSA N